Touch sensitivity in Caenorhabditis elegans
نویسندگان
چکیده
منابع مشابه
Modulation of touch sensitivity in Caenorhabditis elegans
Modulation of touch sensitivity in Caenorhabditis elegans Xiaoyin Chen Sensory perception adapts to diverse environment. Although studies in the last few decades have started to address the question of how sensory systems transduce signals, how these systems cross-modulated is largely unknown. In this thesis, I study mechanosensation in the C. elegans touch receptor neurons (TRNs) to understand...
متن کاملGenetic interactions affecting touch sensitivity in Caenorhabditis elegans.
At least 13 genes (mec-1, mec-2, mec-4-10, mec-12, mec-14, mec-15, and mec-18) are needed for the response to gentle touch by 6 touch receptor neurons in the nematode Caenorhabditis elegans. Several, otherwise recessive alleles of some of these genes act as dominant enhancer mutations of temperature-sensitive alleles of mec-4, mec-5, mec-6, mec-12, and mec-15. Screens for additional dominant en...
متن کاملThe neural circuit for touch sensitivity in Caenorhabditis elegans.
The neural pathways for touch-induced movement in Caenorhabditis elegans contain six touch receptors, five pairs of interneurons, and 69 motor neurons. The synaptic relationships among these cells have been deduced from reconstructions from serial section electron micrographs, and the roles of the cells were assessed by examining the behavior of animals after selective killing of precursors of ...
متن کاملTransducing touch in Caenorhabditis elegans.
Mechanosensation has been studied for decades, but understanding of its molecular mechanism is only now emerging from studies in Caenorhabditis elegans and Drosophila melanogaster. In both cases, the entry point proved to be genetic screens that allowed molecules needed for mechanosensation to be identified without any prior understanding of the likely components. In C. elegans, genetic screens...
متن کاملIdentification of Nonviable Genes Affecting Touch Sensitivity in Caenorhabditis elegans Using Neuronally Enhanced Feeding RNA Interference
Caenorhabditis elegans senses gentle touch along the body via six touch receptor neurons. Although genetic screens and microarray analyses have identified several genes needed for touch sensitivity, these methods miss pleiotropic genes that are essential for the viability, movement, or fertility of the animals. We used neuronally enhanced feeding RNA interference to screen genes that cause leth...
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ژورنال
عنوان ژورنال: Pflügers Archiv - European Journal of Physiology
سال: 2007
ISSN: 0031-6768,1432-2013
DOI: 10.1007/s00424-006-0187-x